Artemisia species are beneficial herbal remedies with antioxidant and anti-inflammatory effects . Dracunculus, belongs to Asteraceae family, display anti-inflammatory and antinociceptive effects . Dracunculus leaf aqueous extract diminished the acute and chronic pain on fructose fed male rats .
Maithili V, Dhanabal S, Mahendran S, Vadivelan R. Antidiabetic activity of ethanolic extract of tubers of Dioscorea alata in alloxan induced diabetic rats. Feng L, Liu W-K, Deng L, Tian J-X, Tong X-L. Clinical efficacy of aconitum-containing traditional Chinese medicine for diabetic peripheral neuropathic pain. Kaur G, Jaggi AS, Singh N. Exploring the potential effect of Ocimum sanctum in vincristine-induced neuropathic pain in rats. Thiagarajan VRK, Shanmugam P, Krishnan UM, Muthuraman A, Singh N. Antinociceptive effect of Butea monosperma on vincristine-induced neuropathic pain model in rats. Muthuraman A, Singh N, Jaggi AS. Effect of hydroalcoholic extract of Acorus calamus on tibial and sural nerve transection-induced painful neuropathy in rats.
Incarvillateine is considered the major active constituent of this plant. Administration of incarvillateine attenuated formalin-induced pain in mice with a higher potency than morphine . Furthermore, the antinociceptive action of incarvillateine attenuated by non-selective adenosine receptor antagonist, non-selective opioid receptor antagonist, and μ and κ opioid receptor antagonists .
Comparative effects of Mitragyna speciosa extract, mitragynine, and opioid agonists on thermal nociception in rats. Hosseinzadeh H, Younesi HM. Antinociceptive and anti-inflammatory effects of Crocus sativus L. Shahraki MR, Mirshekari H, Samadi Z. The nociceptive and anti-Inflammatory effects of Artemisia dracunculus sleep with an onion in your sock L. Winzell MS, Ahrén B. The high-fat diet–fed mouse a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Vincent AM, Brownlee M, Russell JW. Oxidative stress and programmed cell death in diabetic neuropathy. Boyd A, Bleakley C, Gill C, McDonough S, Hurley DA, Bell P, et al.
The virus that causes chickenpox stays dormant in a portion of your spinal nerve root called the dorsal root ganglion. For whatever reason, this otherwise dormant virus gets reactivated — usually by stress — causing a shingles rash. Nerve pain following a case of shingles is called postherpetic neuralgia . Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
Seizures – Gabapentin is sometimes prescribed for dogs with seizures who are not responding well to the main epilepsy medications. Combining these drugs with Gabapentin can sometimes help them work better. Certain disease-modifying treatments for multiple sclerosis have been classified as “… There are no known interactions between ALA and gabapentin, the most common neuropathic pain treatment in those with MS. However, consult your neurologist before supplementing your existing MS treatment program. However, not all of these trials have had such promising findings. A 2017 pilot trial evaluating 51 people with SPMS showed no cognitive benefits — and increased gastrointestinal side effects — among those taking ALA for 12 weeks compared to the participants taking placebos.